This seminar will discuss the concept of Distributed Drug Discovery (D3) and how it adapts basic research to enable, on a global scale, the simple, reproducible and inexpensive synthesis of many potential drug-lead molecules for neglected diseases. D3 has created and published open-source virtual catalogs containing biomimetic molecules accessible by simple and reproducible synthesis in academic laboratories across the world. We have demonstrated this synthetic capability in Indianapolis (USA), Moscow (Russia), Barcelona (Spain) and Lublin (Poland). Collaborators can access these virtual catalogs. When computational analysis identifies promising molecules from them, they can then be readily made by undergraduate students in a distributed fashion. This open-source, integrated process of Distributed Drug Discovery facilitates a direct link between education and drug lead discovery for neglected diseases.

Distributed drug discovery (D3): Linking basic research and education to find drug leads for neglected diseases

240th National Meeting (2010)

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