New synthesis routes for a nanoparticle-based material in which there is controlled, spatial ordering of the nanoparticle (NP) building blocks is of tremendous interest. Various types of ligands have been used to produce nanoparticles ranging from simple organic molecules to oligonucleotides. In most cases for the synthesis of gold nanoparticles, thiol based ligands has been favored invoking the soft metal � soft ligand interaction. Other than sulfur based ligands we have also used ligands bearing N and O as donor atoms. They are of biological importance as they can be used as vehicles for drug delivery to cancer cells. They are a challenge to synthesize as the amino acid nitrogen is not as attracted to the Au metal as its sulfur counterpart. Fluorescence measurements have been performed to study the visible and near IR luminescence. Further investigation is underway to measure the cytotoxicity of these nanoparticles towards cancer cells.

Monolayer protected gold clusters for biological applications

241st National Meeting (2011)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.