Petiveria alliacea L. (Phytolaccaceae) is a perennial shrub indigenous from the Amazon Rainforest, although it can grow in other areas as Tropical and Central America, Caribbean and Southeastern United States. This plant belongs to the Phytolaccaceae family. In folk medicine, Petiveria alliacea is known for its anti-plasmodic, anti-rheumatic, anti-inflammatory and diuretic properties.  In our continuous effort to identify and discover new compounds with potential anti-cancer therapeutic applications, we decided to study this plant order through a bio-guided fractionation using a brine shrimp lethality test.  Leaves and bark were collected, dried and extracted with a mixture of dichloromethane-methanol (1:1). The resulting crude extract was suspended in water and extracted with a series of solvents of different polarity. The cytotoxicity against breast cancer cell lines and chemical analysis of pure products will be presented and discussed.

Biological evaluation and chemical analysis of extracts from p<i>etiveria alliacea</i>

241st National Meeting (2011)

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Biological evaluation and chemical analysis of extracts from petiveria alliacea