Our work is based in the synthesis of gold nanoparticles, and their interaction with amino acids. Four series of Gold nanoparticles were synthesized by reducing the Chloroauric Acid with Ascorbic Acid, Sodium Borohydride, Glucose, Sodium Citrate, and stabilized with Polyethylene Glycol (PEG). A successful synthesis was achieved obtaining a variety of colors from amber, orange, pink, purple, and blue. We described the study of the effect of the addition of selected amounts of Methionine, and Cysteine aminoacids in gold nanoparticles absorption. Two sizes of gold nanoparticles were chosen for this study 12nm and 20 nm. Gold nanoparticles samples were monitored varying the amounts of aminoacids added. Optical properties of gold nanoparticles were measured using a Lambda 25 UV Spectroscopy. Gold Nanoparticles Localized Surface Plasmon Resonance (LSPR) range was between 515nm and 580 nm. Stabilization studies were performed studying variations in the LSPR with time. The AuNP series reduced by ascorbic acid never stabilized with PEG, but were stabilized with styrene. The addition of amino acids to the nanoparticles brought interesting results showing a new band in a wavelength of ~670 nm that was assigned to the interaction with the nanoparticles. This new band increased in intensity according to the concentration of the amino acid added to the nanoparticles.

Synthesis of gold nanoparticles and their application to biomolecules sensing

243rd National Meeting (2012)

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