Silica-coated gold nanoparticles have become an increasingly important research interest due to their tunable surface chemistry, size, and morphology, as well as their high biocompatibility, optical transparency, and controlled porosity.  These silica-coated metal nanoparticles are ideal candidates for many applications, especially surface enhanced Raman scattering (SERS) spectroscopy.  Coating gold nanorods with a thin, homogenous, and optically transparent silica shell should ensure a large surface enhancement while permitting no direct contact with the gold core and the analyte.  A variety of established silica coating strategies are examined, and the quality of the silica shell on the nanorods is determined with respect to uniformity, thickness, and SERS response.

Examination of strategies for silica-coated gold nanorods and the effect of silica shell quality and thickness on SERS response

243rd National Meeting (2012)

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