A noninvasive blood test for screening, detecting and diagnosing of cancers has been seen crucial by clinicians with an interest in cancer, and its delivery as a quest for many researchers. For this reason, detection of cancer biomarkers (e.g. circulating proteins) in the plasma and serum of cancer patients is of great interest. For the demonstration of proof-of-concept of the present point-of-care biosensor, enzyme-based immunochromatographic assay was used as a model. We report here the development of a high sensitive, specific, high positive and negative predictive value (>90%); short assay time (~15 min); low-cost, simple, easy-to-use without complex and expensive instrumentation, and disposable dry biosensor that can be used for protein detection. These features make such biosensor ideal for applications such as breast cancer early diagnosis, rapid screening, point-of-care (POC) detection in hospital laboratories, and even for near-patient or home testing.                                                                        

Development of point-of-care biosensor: A step forward toward breast cancer diagnosis

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.