This paper represents a simplified chemical synthesis of 24-ketolanosterol, a key intermediate in the synthesis of potential C-24 metabolic regulators, to be a potent inhibitor of HMG-CoA reductase activity in mouse L cells grown in a serum-free medium.

Inhibitor of 3-hydroxy-3-methylglutary coenzyme A reductase: Synthesis and activities of 24-ketolanosterol

243rd National Meeting (2012)

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