Bacterial cellulose shows great promise for applications in the biomedical area. The biopolymer is non-degradable, can be steam sterilized and was shown to be highly biocompatible.Due to low thrombogenicity and high mechanical stability, bacterial cellulose tubes may even be suitable for small diameter blood vessel replacement.We present a novel method utilizing Gluconacetobacter xylinus to produce bacterial cellulose tubes in a reliable and reproducible way. The produced tubes show high mechanical stability. The radial stress at break and the suture pull out strength where evaluated. Tubes were shown to be homogeneous over the length. The wall of the tubes was shown to consist of radially spaced layers, thus providing a high safety margin against burst. Preliminary animal experiments were conducted in pigs. Tubes replaced a part of the arteria mesenterica superior.

Production of bacterial cellulose tubes with <i>Gluconacetobacter xylinus</i> by a novel method

243rd National Meeting (2012)

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Production of bacterial cellulose tubes with Gluconacetobacter xylinus by a novel method