Pharmaceutical counterfeiting is a serious problem facing developing nations. Inadequate or inappropriate antibiotics may lead to insufficient treatment of infected individuals as well as to an increased rate of antimicrobial resistance. The PADs team is developing simple colorimetric tests to semi-quantitatively and qualitatively determine the validity of an antibiotic sample. PAD-based tests are designed to be stable on paper and develop results rapidly. They are intended to be inexpensive to produce and easy to perform, even in non-laboratory environments. The PAD is impregnated with colorimetric indicator reagents, and then exposed to the pharmaceutical analyte to verify active ingredient concentration. Antibiotic directed PADs will test for Cloxacillin, Erythromycin and other commonly prescribed agents. These and other PADs may improve health care in multiple settings including developing nations.

Developing simple colorimetric verification tests for antibiotics on PADs (Paper Analytical Devices)

243rd National Meeting (2012)

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