Among the C3 symmetrical host molecules, two classes are built from cyclotriv�ratryl�ne (CTV) unit (figure 1-(a)): cryptophanes and hemicryptophanes (figure 1-(b) and (c) respectively). Figure 1. <img src='https://acs-archive-assets2.s3.amazonaws.com/239nm/uploads/17237_carbazole_nnn_complex.jpg' alt='' /> The cryptophane hosts, which are constructed from two cyclotriveratrylene (CTV) units, can encapsulate a wide variety of guests, and have remarkable binding properties toward neutral or charged guests and efficient chiral recognition properties. The hemicryptophanes, combining a CTV unit with another C3 symmetrical moiety, are ditopic host molecules. Although their synthesis was described for the first time by A. Collet and J.-M. Lehn in 1982, their complexation properties and their catalytic activities have received little attention so far.Here, we will described new aspects of the chemistry of hemicryptophanes since recently they were found to be efficient supramolecular catalysts, ion-pairs, zwitterions, or enantioselective carbohydrates receptors, and led to the design of novel molecular mechanical components as propellers or gyroscope.

Revival of the chemistry of hemicryptophanes

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.