The goal of this experiment is to design a laboratory experiment that uses thin layer chromatography (TLC) to identify the separate components of certain over-the-counter drugs.  TLC is a characterization technique used to identify how many components are in a substance and to match the identity of a compound with a known substance.  In this research, TLC was used to identify the different compounds of three over-the-counter drugs: Benadryl, Benadryl D, and Sudafed PE.  These three drugs all contain variations of the components diphenhydramine HCl, and phenylephrine HCl.  The retention factor values were recorded and each component was identified.

TLC of over-the-counter drugs

243rd National Meeting (2012)

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