Pyrrolizidine alkaloids (PA's), potentially toxic natural secondary products, are typically found in the plant family Asteraceae.  As a member of the family, genus SenecioSenecio mohavensis should be expected to contain PA's.  An alternate name for pyrrolizidine alkaloids is senecio alkaloids.  , an unusual annual North American species gathered from the Mohave Desert is a previously unstudied species of Senecio.   Preliminary TLC and GC/MS investigation of S. mohavensis suggested the presence of four PA compounds, including the major component tentatively as senecionine and three minor unknown PA's.  Further chromatographic and instrumental analysis will allow us to determine the structure of the unknown PA's, as well as establish the major PA as senecionine.

Determination of pyrrolizidine alkaloids from <i>Senecio mohavensis</i>

243rd National Meeting (2012)

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Determination of pyrrolizidine alkaloids from Senecio mohavensis