The development of novel biodegradable elastomers has not only facilitated the emergence of unique medical therapies, but has also addressed concerns regarding the persistence of plastics in the environment.  Unfortunately, many of these materials are prone to bacterial colonization due to the fact that their degradation products are potential nutrient sources for microbial organisms.  As such, the development of degradable elastomers that possess adequate antibacterial properties is a crucial aspect for the implementation of absorbable materials in numerous applications such as packaging materials for food and medical products and use as medical implants.  We report the development and evaluation of novel poly(diol citrate) elastomers with tethered quaternary ammonium biocides.  The influence of elastomer structure on resulting mechanical, degradation, and biocidal properties are evaluated and discussed with respect to potential applications.

Degradable poly(diol citrate) elastomers with tethered quaternary ammonium biocides

243rd National Meeting (2012)

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