In this talk we will present two new approaches to study interfaces of biological relevance in situ and in vivo. The first is the investigation of phospholipid multilayers under pressure and shear stress. We built a dedicated Neutron Reflectometer 'BioRef' at the Neutron source at Helmholtz Center Berlin for Materials and Energy which combines neutron reflectivity and IR Reflection Spectroscopy to probe the mechanical and temperature effects on the stability and phase transitions in lipid multilayers. The second example refers to the use of Sum Frequency Generation Spectroscopy to measure ordering phenomena within the extracellular matrix of living adherent cells.

Probing the liquid/solid interface with neutrons and non-linear optical techniques

243rd National Meeting (2012)

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