Nanofibers have interesting characteristics such as large surface area to volume ratio, flexibility, and superior mechanical performance.  As a result, these fibers are used in many important applications such as drug delivery systems as well as tissue engineering. The most efficient technique for preparing nanofibers is electrospinning. Nanofibers consisting of polyacrilonitrile and polylactic acid (PLA) with several different nanoparticles were prepared and characterized using an optical and a scanning electron microscope (SEM).  By varying the concentration, voltage, flow rate, and distance between the needle tip and collector plate of the precursor solutions, favorable nanofibers were obtained. PLA is a coagulant that resembles the extracellular matrix. Thus electrospinning with inert nanoparticles provides an ideal method of delivery for drugs to target cells. Drugs are now able to be released to target cells controllably which decreases side effects. This provides an economic benefit in drug synthesis as well as for the consumer

Preparation and characterization of polyacrilonitrile (PAN) and polylactic acid (PLA) electrospun nanofibers and nanoparticle embedded nanofibers using optical and scanning electron microscopy

243rd National Meeting (2012)

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