Technetium chemistry is complicated. The 2012 recipient of the Seaborg Award, Professor Silvia Jurisson, was one of the first inorganic chemists to elucidate the chemistry of this fascinating transition metal starting as a graduate student. Her inspirational work elucidated the coordination chemistry and provided understanding of the redox chemistry of Tc-99m drugs that are clinically used.  The presenter of this seminar and Professor Jurisson have a combined fifty plus years working with technetium.   First, working together at Squibb, we identified and developed Tc-99m complexes for diagnostic imaging. Subsequently we took independent paths that were connected in a quest to understand the complex redox chemistry of Technetium and its third row congener, Rhenium.  These studies have applications in identification of materials for stabilization of Tc-99 that is a byproduct of uranium fission and found in the environment.  Also, this work finds application in identifying ligands for stabilization of Rhenium-186 and Rhenium-188 for radiotherapy applications.   Case studies in technetium-99m drug design and in understanding the complex chemistry of technetium-99 incorporated into redox active metal oxide materials will be discussed in this seminar as inspired by Professor Jurisson.

Fifty plus years of technetium (2.5 x 10<sup>-4</sup> of the half life of Tc-99)

243rd National Meeting (2012)

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Fifty plus years of technetium (2.5 x 10-4 of the half life of Tc-99)

Fifty plus years of technetium (2.5 x 10^-4 of the half life of Tc-99)