The inorganic and radiochemistry of technetium, rhenium, rhodium, gold, the lanthanides, gallium, indium, arsenic and others have been and continue to be investigated for potential medical, environmental and biological applications. Both the bifunctional chelate approach (Rh-105, Au-199, radiolanthanides) and the integrated approach (Tc-99m, Re-188) have shown utility for targeting receptors on tumor cells (e.g., melanoma, prostate cancer). Understanding the basic chemistry of technetium with sulfide may lead to improved methods for separations and storage in nuclear fuel cycle chemistry as Tc-99 is a fission product. Development of high specific activity radionuclides (e.g., Rh-105, Re-186, As-72) may yield a larger suite of potential radiotherapeutic or radiodiagnostic agents. Probing plant biochemistry with radiotracers may lead to understanding metal ion transporters and/or potential phytoremediation. Radiotracers have applications in many scientific arenas and continue to lead to new and interesting discoveries.

Award Address  (Glenn T.   Seaborg Award for Nuclear Chemistry sponsored by the ACS Division of Nuclear   Chemistry and Technology). Radiochemistry adventures: Medical, environmental and biological applications of radiotracers

243rd National Meeting (2012)

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