Using a 1, 3, 5, 7, 8-pentamethylpyrromethene-boron difluoride (BODIPY) derivative has been shown to be an efficient method for the capture of fluoride ions in organic media. Furthermore, the synthetic versatility and the fluorescence properties of the BODIPY core make it a suitable option for the synthesis of water soluble derivatives and a dual mode tag. Recently, the ability of a DMAP substituted BODIPY core has been shown to capture F18 in acetonitrile with excellent RCY and RCP.  Work is currently focused on developing a labeling synthon for plant signaling peptides in the form of an 8-carboxy phenone NHS ester.

Development of a dual mode (PET/fluorescence) tag for monitoring plant-signaling peptides

243rd National Meeting (2012)

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