Organometalic compounds (e.g., organolithiums) are among the most useful reagents in organic synthesis. Metallosilanes should play a similar role in organosilicon synthesis. Yet, despite their great synthetic potential, the number and variety of metallosilanes is small and the knowledge of their structures and reactivity is very limited.In this lecture we report the synthesis of several novel metallosilanes shown below (Figure 1). They include: tris-silyl substituted-E-lithiums (1), functionalized silyl lithiums (2), the first lithiosilenides 3 and geminal dimetallosilanes 4-6. We also discuss some of the reactions of these compounds and their applications in the synthesis of new organosilicon compounds, such as silenes (R2C=SiR'2) and a-silapeptides.

Novel metallosilane reagents and their reactions

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.