. Purification is usually the most expensive portion of a protein manufacturing process. Crystallization permits to streamline protein purification processes. Protein purification by crystallization as an alternative tool offers a number of benefits such as eliminating a number of columns, decrease the time taken for purification, decreasing the volume to handle, no sophisticated equipments, and overall reduction in cost of manufacturing. Protein crystals are more pure, more stable and more concentrated than soluble material. Protein crystals allow substantial savings on purification columns, eluants and processing time. The crystallization process can be easily scalable to 30 � 50 kg. ProCrysta technology allows the inexpensive crystallization of protein right from the broth of a fermentor in bacterial or fungal fermentation, from cell culture media and from transgenic sources. ProCrysta provide services for the development of both research and scaling up of the crystallization process.

Protein purification and analyses

243rd National Meeting (2012)

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