We have developed a chemo- and regioselective palladium-catalyzed procedure for allylic C-H bond functionalization under mild conditions (typically at 40-60�C in MeCN). In this procedure we have used a sodium perborate/carboxylic acid anhydride mixture as a combined oxidant and source of nucleophile. The scope of the reaction is wide, tolerating many functional groups; both terminal and internal alkenes can be functionalized. The reaction is very robust, proceeding under air in non-dry solvent.

Highly selective C-H acyloxylation using environmentally benign sodium perborate

243rd National Meeting (2012)

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