Ewing's Sarcoma is a specific bone cancer within the Ewing's family of tumors and affects approximately 200 children and young adults each year in the United States. The cancerous tumor originates in areas of the skeletal system and quickly metastasizes from the bone to the lungs and other body parts via the circulatory system. Ajulemic acid is a synthetic derivative of tetrahydrocannabinol (THC), the active compound in marijuana, and contains the healing properties of marijuana without the psychotropic side effects typical of this drug. Ajulemic acid has been found to effectively induce apoptosis in Ewing's sarcoma tumors. Just as different people respond to the same drug in a variety of ways, this experiment seeks to discover the responses of different Ewing's sarcoma cell lines to ajulemic acid. We have also investigated this drug's efficacy against other pediatric tumor lines.

Treatment of Ewing's sarcoma RDES cell line with ajulemic acid

243rd National Meeting (2012)

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