We have taken a major chemistry reference work in print and designed an interactive Web version from first principles. The online product combines full-text browsing functionality together with InfoChem's modern structure and reaction search capabilities. Science of Synthesis  is a unique, structure/reaction searchable, full-text resource that provides the user with expert-evaluated methods and reactions.Science of Synthesis  covers synthetic methodology developed from the early 1800s to-date for the entire field of organic and organometallic chemistry. World-renowned chemists have chosen important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The logical, structured order of content within Science of Synthesis  means that it is simple to gain an overview of the wider context in a particular subject field.The user can search for specifically defined full-text fields and advanced text searching options are available. It is possible to search the manually prepared named reaction index, which associates transformations with specific named reactions even if they are not mentioned as such in the full text i.e. deep indexing.A number of filters, called fields are available allowing the hitlist to be refined. The hitlist generated by a text search can be filtered depending upon the location in the full text that the result occurs e.g. in the title, full text, or references. It may also be sorted by relevance - using an algorithm that weights the text results � or by publication date.The hitlist generated by a structure search may be filtered by the role of the structure e.g. product, catalyst, or solvent. It may also be filtered by the best match criteria (exact or substructure result). The hitlist itself is ordered by relevance, using an internal algorithm that weights exact structure and substructure results. Sophisticated search operators (rating!) allow for efficient and convenient reaction searching.

SOS 4.0: Advances in text, structure, and reaction searching

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.