Disposable technologies are becoming popular process strategies particularly in the area of upstream processing in the manufacturing of biopharmaceuticals. Natrix Separations is developing a completely disposable hydrogel based chromatographic solution from capture to polishing steps in the downstream processing of monoclonal antibodies as well as other biotherapeutics. This study presents the data on binding capacity, selectivity and throughput of Natrix hydrogel platform based ion-exchange and hydrophobic interaction media for the purification of monoclonal antibody from a representative feed stream.

Single-use high performance chromatographic media: Purification of monoclonal antibody in bind and elute mode

243rd National Meeting (2012)

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