The need for new agrochemicals remains constant due to the ever-changing composition of crop pests, increasing environmental requirements, and the development of resistance to existing crop protection agents, coupled with the need to provide adequate food supply for an expanding world population. There is a diverse and evolving set of approaches to the discovery of new agrochemicals including natural products, combinatorial chemistry and high throughput screening, exploring novel chemistry and bioactive scaffolds, QSAR and pharmacophore modeling, and structure-based design. Examples of different approaches, current and historical, relating to the discovery of new agrochemicals will be discussed.

"What if" approaches to agrochemical discovery

244th National Meeting (2012)

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