Methicillin-Resistant Staphylococcus aureus (MRSA) is responsible for up to 19,000 annual US deaths via this skin infection. MRSA is a strain of Staphylococcus aureus, a bacterium which produces a biofilm necessary for its survival and proliferation. Studies have shown that the serine protease ESP from S. epidermidis can destroy the formation of this biofilm. We examined the effectiveness of various compounds on both the prevention and destruction of the such as the supernatant from S. epidermidis and Biotene mouth wash. S. aureus was cultured and treated with Biotene PBF, Biokleen, Propolis and serine protease from S. epidermidis compounds.  Our results indicate that Propolis did not show any impact on the biofilms.  Results from S. epidermis serine protease treatment were not conclusive.  However, the Biotene PBF mouthwash treatment was the most effective in the destruction of biofilm whereas Biokleen treatment had the most impact against preventing the formation of biofilm.

Effect of various compounds on the prevention and degradation of staphylococcus aureus biofilms

244th National Meeting (2012)

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