2-Pyridones are interesting structures that display widespread biological characteristics. The thiazolino ringfused bicyclic 2-pyridones in particular show biological activities against pili assembly in uropathogenic E-coli as well as curli assembly. To further study these systems synthetic routes to fluorescent thiazolino ringfused bicyclic 2-pyridones marked with either a BODIPY or coumarin fluorophore in position 7 or 8 has been developed.

Synthesis of fluorescent thiazolino ringfused bicyclic 2-pyridones

244th National Meeting (2012)

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