Antibiotic counterfeiting is a serious problem facing many developing nations. Inadequate dosing may lead to insufficient treatment of infected individuals and an increased rate of antibiotic resistance. The antibiotics division of the project team is developing a series of simple colorimetric tests on PADs (paper analytical devices) to semi-quantitatively and qualitatively analyze antibiotics samples in a non-laboratory environment. The PAD is impregnated with colorimetric indicator reagents, and then exposed to the pharmaceutical analyte to verify active ingredient concentration and check for common counterfeiting agents. This division of the project team has focused its efforts on developing general PADs for types of antibiotics such as macrolides as well as more specific PADs for drugs such as erythromycin-A. These and other PADs may improve health care in multiple settings including developing nations.

Simple field analysis of antibiotics: The PADs project, antibiotics division

244th National Meeting (2012)

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