Palladium(0) can catalyze the intramolecular addition of an aryl and halogen group across an alkene. This carbohalogenation reaction features completely atom-economical carbon-carbon bond formation. The use of a palladium catalyst with bulky phosphine ligands is found to be crucial for high reactivity. Mechanistic details and recent synthetic advances will be discussed.

Palladium-catalyzed carbohalogenation of alkenes

244th National Meeting (2012)

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