Owing to their unusual behaviors compared with spherical gold nanoparticles as well as corresponding bulk materials, gold nanorods provide tremendous opportunities as well as challenges for insights in fundamental science that opens the door to applications such as optics, sensors, biological imaging and anticancer agents. So far gold nanorods are mainly prepared in an aqueous solution by a seed-mediated growth method, in which cetyltrimethylammonium bromide (CTAB) is widely used as a shape-directing surfactant to selectively form a densely packed dynamic layer around the sidewall of a growing gold nanorod with its two ends free from CTAB for an anisotropic growth along the longitudinal axis. The resultant gold nanorods covered with CTAB layer on their longitudinal surface are water-soluble. Unfortunately, the dynamic CTAB layer is not stable. For example, with the removal of excess free CTAB and other components in aqueous solution by centrifugation to obtain the CTAB-covered gold nanorods, the bound CTAB in the dynamic layer will eventually enter the solution, which will result in irreversible aggregation of gold nanorods into bulk gold. Preparation of water-soluble and stable gold nanorods via S-Au covalently bonding modification would be important for their biological applications. Here we will represent our recent effort on water-soluble supramolecular rotaxane monolayer protected gold nanorods.1Supported by the Air Force Office of Scientific Research (FA9550-09-1-0254)

Water-soluble supramolecular rotaxane monolayer protected gold nanorods<sup>
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244th National Meeting (2012)

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