Hollow colloidal capsules were filled with the payload and sealed with a DNA zipper based mechanism trapping the payload inside. The capsules were opened by the detection of a specific DNA trigger sequence. The interaction of the capsule with the trigger sequence resulted in the release of the drug. The construction protocols of the DNA zippers and the capsules are presented together with SEM, DLS and Fluorescence data.

Nanocapsule that delivers their payload by interaction with a DNA trigger

244th National Meeting (2012)

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