The prevention of caries continues to remain a prominent concern among dental professionals. Although products such as toothpaste, mouthwash, and sealants have all targeted this process, the challenge against primary and secondary caries still persists. This study provided a distinctive approach through the creation of a ubiquitous platform capable of being incorporated into several types of dentrifices. Solvated calcium, fluoride, and phosphate salts were encapsulated in ion permeable microcapsules and loaded into rosin and resin based varnish formulations. The role of initial salt concentration in the microcapsule, w/w% loading, microcapsule chemical structure, ion type and continuous phase on the ion release rate was studied.  It was concluded that varnish formulated with microcapsules released calcium, phosphate and fluoride ions in a biologically available form with a controlled rate of release.

Ion permeable microcapsules: An approach for remineralization

244th National Meeting (2012)

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