Nanodiamond powder is one of the most promising carbon nanomaterials for biomedical and composite applications[1]. Nanodiamond is made of ~5nm diamond particles with large accessible surface and tailorable surface chemistry; has unique optical, mechanical, and thermal properties; and is non-toxic. To fully exploit the potential of nanodiamond in drug delivery, biomedical imaging, and nanocomposites, attention must be paid to its purity, surface chemistry, and dispersion quality. Surface modification of nanodiamond for several composite and biomedical applications will be discussed. Linking of octadecylamine improves dispersion of nanodiamond in hydrophobic polymers. Reactions of nanodiamond functional groups with polymers bring the nanocomposite design to a new level, allowing for creation of covalent nanofiller-matrix interface with designed properties. For tissue engineering scaffolds, non-toxic fluorescent nanodiamond introduced into biodegradable polymers provides increased strength, visual monitoring, enhanced biomineralization, and release of growth factors and antibiotics attached to its surface. In drug delivery, rational surface modification allows for enhanced adsorption and chemical binding of drugs with sustained or triggered release.Mochalin, V. N.; Shenderova, O.; Ho, D. Nature Nanotechnol. 2012 , 7, 11-23.

Surface modification of nanodiamond for biomedical and composite applications

244th National Meeting (2012)

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