Epigallocatechin gallate (EGCG) is one of the most abundant and potent antioxidants found in green tea. Research has shown that this compound displays many cancer preventative effects on cells. EGCG contains many hydroxyl functional groups that can be converted to ester groupings by chemical derivatization to make the molecule more hydrophobic. This may increase cell permeability of EGCG and possibly increase its potency. In this study, we compared the biological effects of EGCG and ECGG-peracetate on a cancer cell line A431 by assessing the respective cellular response caused by each of these two compounds with a quartz crystal microbalance with dissipation monitoring.

Investigating structural changes to green tea extract (EGCG) by monitoring the effect on cells using QCM-D

244th National Meeting (2012)

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