Paper is emerging as an ideal material for low cost biosensor platforms. In this work, the surface and morphology of paper are engineered to amplify the Surface Enhanced Raman Scattering (SERS) signal. The attachment of gold nanoparticles (AuNPs) to paper substrates represents a promising new method to produce low cost, rapidly-produced, flexible and sustainable sensors for health and environmental applications. Whilst the ability to absorb AuNPs on paper has previously been demonstrated, there have been few reports relating to the effect of paper morphology and post-treatments on the adsorption state of the nanoparticles to achieve the desired structures and property enhancements. The main goal of this work is to manipulate the aggregation state of colloid such as AuNPs by engineering the surface charge of paper using cationic polymers of different concentration and charge density. The relative aggregations of AuNPs have a drastic effect on SERS signal amplification, contributing to their potential applications as efficient biodiagnostic sensors.Keywords:  Gold nanoparticles, cationic polymers, paper substrate, SERS.

Gold nanoparticles-SERS for paper biodiagnostics applications

244th National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.