Highly versatile tetradentate N2S2 ligands bind to numerous transition metals and, as the Cys-X-Cys motif in proteins, play important roles in metalloenzymes such as Acetyl CoA Synthase and Nitrile Hydratase.  We have contributed to extensive studies of M(N2S2) using various metals such as nickel, palladium, and iron with di- and tetraanionic N2S2 donor ligands, and are currently examining such sites with paramagnetic ions such as [V=O]2+ and Mn2+.  With its d1 electronic configuration, [V=O]2+ has served as a useful EPR active spin probe in bioinorganic chemistry.  The extent of the tripeptide motifs that produce biological N2S2 binding sites can thus be explored by [V=O]2+ incorporation.  These model complexes permit comparison of the structural and electronic properties of these complexes with our family of [(N2S2)M] complexes where M = Ni2+, Pd2+, ZnCl+, etc.The synthesis and characterization of neutral and dianionic N2S2(V=O) complexes has recently been reported.1 The ability of the M(N2S2) complexes to bind exogenous metals through the cis-dithiolato sulfurs offers an additional route to exploration [V=O]2+ ions spin labeling ability.  To be reported are magnetic and electrochemical properties of [V=O](N2S2)�MLx heterobimetallic adducts where MLx are {Fe(NO)2}9 and W(CO)5,4. 1. Jenkins, R. M. et al. Inorg. Chem. 2011  , 50, 1849-1855.

Paramagnetic transition metal ions in N<sub>2</sub>S<sub>2</sub> coordination

244th National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.

Paramagnetic transition metal ions in N2S2 coordination

Paramagnetic transition metal ions in N₂S₂ coordination