Pyrazinones with a variety of heteroatom-containing substituents at the 2-position exhibit potent fungicidal activity.  Amides which are bonded to the ring through either nitrogen or carbon retain high levels of broad-spectrum activity. Methods to synthesize these compounds will be presented along with a summary of the biological activity and structure-activity relationships of this class.

Fungicidal pyrazinone-2-carboxamides

244th National Meeting (2012)

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