The pyridazinone ring system has proved to be a rich source of leads for the discovery of crop protection products.  We have found that 4-piperazinyl and 4-piperidinyl substituted pyridazinones have insecticidal activity against Lepidopteran insects.  Synthetic methods to prepare these compounds will be presented along with a summary of the biological activity and structure-activity relationships of this class.

Insecticidal 4-piperazinyl pyridazinones

244th National Meeting (2012)

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