Drug Discovery and Development is a challenging and complex process that involves the dedicated multidisciplinary efforts of many discovery and development functions. Despite of the breakthroughs in innovations and process refinements that have dominated drug discovery during the last two decade, the number and diversity of new chemical entities (NCE's) approved for human use has not kept pace from the 1980's to now.  Pharmaceutical industry is currently facing enormous challenges, such as reduced efficiencies, declining innovation and the industry's perceived tarnished image. There is a clear need for change in the paradigms designed to address these challenges. While Pharma have embarked on a range of initiatives, other sectors have also responded. Several academic drug discovery centers have also recently been established to facilitate the transition of innovative academic ideas and breakthroughs into attractive drug discovery opportunities. The presentation will highlight challenges facing the pharmaceutical industry with emphasis on the impact of chemical sciences and academic Drug Discovery Centers in addressing the innovation gap.

Strategies for the discovery of innovative therapeutics

244th National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.