The vinyl group is of fundamental importance in organic chemistry. Vinyl heterocycles are widely used in the preparation of functional materials due to the propensity of aryl vinyl system to participate in variety of reactions such as cycloaddition, cyclopropanation, and metathesis processes.  We have developed a expedient synthesis of 6-6 and 6-5 fused vinyl heterocycles possessing synthetically versatile vinyl handle adjacent to the ring junction starting from commercially available 2-amino heterocycles such as pyrimidine, pyridines or thiazoles and 2,4-dichloro-but-2-yne in moderate to good yields. The results will be presented.

Facile synthesis of vinylimidazo heterocycles and their application in organic synthesis

244th National Meeting (2012)

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