We report on sum-frequency generation spectroscopy to investigate biomolecular interaction specifically at membrane interfaces. Two applications will be highlighted - the first providing new insights into amyloid fibril formation - and suppression - at model membrane interfaces, the second shedding new light on DNA-lipid interactions, and in particular the role of water in that interaction.

Label-free spectroscopy of lipids, proteins, and protein fibrils at model membranes

244th National Meeting (2012)

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