In the past several decades there has been a tremendous effort in the development of hybrid biological-electronic sensor systems that allow a more comprehensive understanding of the retina. Current techniques of neural sensing employ electrode arrays that are typically large in size and utilize direct current measurements, leading to limited resolution and retinal tissue damage. The work presented here shows a novel sensing approach and development of a prototype device that relies on capacitive coupling between unique 3D semiconductor electrode probes and neural tissue to measure electrical activity in the retina due to light stimulation. Specifically, design and microfabrication of the semiconductor device is described and interfacing of this device with retina is demonstrated. The work being presented provides a base for implementation of semiconductor probe technologies in robust (bio)molecular sensing devices that study the dynamic function of retinal-neuronal networks.

Design and fabrication of a 3D pillar electrode array for transduction of retinal responses

245th National Meeting (2013)

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