In the recent era, significant development has been achieved in the research field based chitosan hydrogels for bone tissue engineering. In the present study, we have prepared and analyzed different kind of hydrogels by the combination of carbon nanotube and collagen with chitosan, and also in vitro biomineralisation was (hydroxyapatite coating) attained on the hydrogels by stimulated body fluid. The prepared hydrogels are chemically characterized, and in vitro studies are performed with osteoblastic (MC3T3-E1) cell line and in vivo study. The obtained results infer that the prepared hydrogels are non-toxic and higher proliferation was observed on the ternary hydrogels. As the conclusion, by the addition of collagen, carbon nanotube and hydroxyapatite in the chitosan hydrogel, improved properties was observed to mimic the nature function of bone.

?Chitosan based hydrogels for bone tissue engineering

245th National Meeting (2013)

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