Biomedical Research is fundamentally the pursuit of dual goals: to advance our understanding of the world around us, and to apply that understanding toward improving the quality of our existence in that world. Chemists work to meet these goals by designing and manipulating molecular structures, with broad applications in fields such as drug discovery.Our chemistry group at UT Southwestern Medical Center is interested in three general areas of research. We synthesize biologically active natural products (especially polycyclic alkaloids). We develop new catalytic stereoselective reactions (with an interest in enantioselective molecular rearrangements). We also integrate our work in these two areas into medicinal chemistry collaborations for the discovery of novel therapeutic agents.In this seminar, I will discuss some of our recent chemical discoveries in the context of biomedical research. I will also describe my experiences as a synthetic chemist at a medical center.

New chemical discoveries in a medical center

245th National Meeting (2013)

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