We present here our work on developing a long-lasting bacteriostatic copolymer, vinylbenzyl-Thymine and vinylbenzyl triethylammonium Chloride (VBT-VBA), which can be applied to surfaces in hospitals. Bacterial infections acquired during patient stay in the hospital have been a long-standing problem. Recent studies have shown the antibacterial action of substituted VBT-VBA polymers against E.coli. We are examining the effect on growth these polymers have against 6 other pathogenic bacteria commonly acquired in hospitals. We will also be developing new methodology to perform these antibactierial assays at high-throughput using a 96 well plate assay, utilizing the recently purchased ViaFlow robotic liquid handler. The outcome of this work may lead to the development of a commercial product that will dramatically decrease the number of bacterial infections that patients receive from hospitals.

Analyzing the antimcrobial properties of bacteriostatic copolymer, vinylbenzyl-thymine and vinylbenzyl triethylammonium chloride via 96-well assay

245th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.