Antiobiotics and other pharmaceuticals containing a basic site can be easily conjugated to alginic acid through an acid-base reaction. The resulting polymer can then be used to prepare non-woven mats by electrospinning with a copolymer such as PVA. Presented here is an examination of antibiotic release from these materials by a simple ion exchange pathway and its effectiveness in inhibiting bacterial growth. Applications to wound treatment and pain management are also discussed.

Antibiotic delivery from electrospun non-woven mats

245th National Meeting (2013)

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