Lab-on-a-chip devices (LoC) offer detailed control over colloidal systems, complex reaction networks, cells, and small organisms. Integration of NMR spectroscopy into LoC is attractive, but challenging in terms of sensitivity and resolution. We have recently shown that highly resolved spectra can be obtained from LoC by integration of a passive radiofrequency resonator, along with careful design of the fluidic network to avoid susceptibility broadening. The approach offers new opportunities, including the incorporation of hyperpolarisation techniques into LOC NMR devices.

Integration of high-resolution NMR into lab-on-a-chip devices for the study of complex systems

245th National Meeting (2013)

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