The potential of Salen type ligands applicability in the medical world is increasingly being uncovered. Unfortunately, most Schiff base complexes are not water-soluble. This poses a problem for designing bioavailable drugs or pro-drugs. The water soluble ligand, Na2[5,5-sulphonatosalen], was synthesized and metalated with nickel, zinc, and copper for testing biological activity in bacteria. The syntheses and spectroscopic characteristics will be discussed.

Synthesis and characterization of water soluble salen ligand for biological testing

245th National Meeting (2013)

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