The objective of this study was to develop a biocompatible and biodegradable polymer shell on superparamagentic manganese ferrite nanoparticles for biomedical applications. Hydrophobic manganese ferrite nanoparticles of the mean crystallite size less than 10 nm were prepared through thermal decomposition of organometallic precursors in benzyl ether in the presence of oleic acid as a surfactant. A sample of manganese ferrite nanoparticles with 5.0 nm size exhibited the block temperature of 150K and magnetization of 38 emu/g at 300 K and the external field of 50 kOe. The hydrophobic nanoparticles were converted to water soluble via the treatment with a amphoteric surfactant, CTA-GAT (CTA = cetyltrimethylammonium and GAT = tris-glutaric anhydride). Polymerization on the surfaces of the manganese ferrite nanoparticles was carried out using sebacoyl chloride as cross-linker. The cross-linking of �OH groups by sebacoyl chloride on the surfaces was studied by infrared spectroscopy.

Polymer coated superparamagnetic manganese ferrite nanoparticles

245th National Meeting (2013)

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