During IR spectroscopy, bonds within a molecule absorb electromagnetic pulses at frequencies which are identical to their vibrational frequency.  Analyzing the combination of those frequencies and their strength give insight into functionality present, and the overall structure of a molecule of interest. Several functional groups, including azides, amides, esters, and ketones, create strong, characteristic IR peaks.  Two-dimensional infrared spectroscopy (2DIR) is an important and emerging new tool to provide valuable information regarding the spatial interaction between these same functional groups that are probed with traditional IR spectroscopy.  In order to better understand intramolecular energy transfer between functional groups, probe compounds containing these characteristic functional groups were created for 2D IR spectroscopic analysis.  These probes compounds consisted of an azide functionality connected via covalent bonds to a methyl ester functionality via a spacer consisting of methylene units.  In order to better understand the distance dependence of this energy transfer between functional groups, the length of the carbon chain was varied between 3 and 12 methylene units separating the functionalities of interest.

Synthesis of model compounds for 2D IR spectroscopic analysis

245th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.